List of conditions Cancer All cancer patients actively receiving (and/or within 6 weeks of receiving) systemic therapy with cytotoxic chemotherapy, targeted therapy, monoclonal antibodies or immunotherapies and radical surgery or radiotherapy for lung or head and neck cancer. All patients with advanced/metastatic cancers.
Chronic kidney disease Chronic kidney disease, on dialysis, or eGFR <15 ml/min.
Chronic neurological disease or condition Chronic neurological disease or condition with evolving ventilatory failure (requiring non-invasive ventilation), for example: motor neurone disease, spinal muscular atrophy.
Chronic respiratory disease Chronic severe respiratory disease, for example: severe cystic fibrosis, severe COPD, severe pulmonary fibrosis.
Diabetes Diabetes and HbA1C ≥58mmol/mol
Immunocompromised Severe immunocompromise due to disease or treatment, for example: · transplantation: - Listed for solid organ or haematopoietic stem cell transplant (HSCT) - Post solid organ transplant at any time - Post HSCT within 12 months · genetic diseases: - APECED** - Inborn errors in the interferon pathway · treatment: - included but not limited to Cyclophosphamide, Rituximab, Alemtuzumab, Cladribine or Ocrelizumab in the last 6 months
Inherited metabolic diseases* Disorders of intermediary metabolism/at risk of acute decompensation, for example: Maple Syrup Urine Disease.
Intellectual disability* Down Syndrome.
Obesity BMI >40 Kg/m2. Sickle cell disease*
COVID-19 Vaccination Rollout Programme - Group 7 Those aged 18 to 59 years in a High Risk Group;
Cancer Haematological - within 1 year. Haematological - within 1 - 5 years. Non-haematological - within 1 year. All other cancers on non-hormonal treatment.
Chronic kidney disease Chronic kidney disease with eGFR <30ml/min.
Chronic liver disease Chronic liver disease, for example: cirrhosis or fibrosis.
Chronic neurological disease or condition Chronic neurological disease or condition significantly compromising respiratory function and/or the ability to clear secretions, for example: Parkinson's disease, cerebral palsy.
Chronic respiratory disease Other chronic respiratory disease, for example: stable cystic fibrosis, severe asthma (continuous or repeated use of systemic corticosteroids), moderate COPD.
Diabetes All other diabetes (Type 1 and 2). Immunocompromised Immunocompromise due to disease or treatment for example: high dose systemic steroids (as defined in Immunisation Guidelines for Ireland Chapter 3), persons living with HIV. Inherited metabolic diseases*
Disorders of intermediary metabolism not fulfilling criteria for very high risk.
Intellectual disability* Intellectual disability*** excluding Down Syndrome.
Obesity BMI >35 Kg/m2.
Severe mental illness* Severe mental illness, for example: schizophrenia, bipolar disorder, severe depression. *additional or updated medical conditions **
WHO definition of intellectual disability as “impairments in adaptive, social, and intellectual functioning (IQ<70), requiring daily support, with onset in the developmental phase evelopmental phase (<18 years)”