List of conditions Cancer All cancer patients actively receiving (and/or within 6 weeks of receiving) systemic therapy with cytotoxic chemotherapy, targeted therapy, monoclonal antibodies or immunotherapies and radical surgery or radiotherapy for lung or head and neck cancer. All patients with advanced/metastatic cancers.
Chronic kidney disease Chronic kidney disease, on dialysis, or eGFR <15 ml/min.
Chronic neurological disease or condition Chronic neurological disease or condition with evolving ventilatory failure (requiring non-invasive ventilation), for example: motor neurone disease, spinal muscular atrophy.
Chronic respiratory disease Chronic severe respiratory disease, for example: severe cystic fibrosis, severe COPD, severe pulmonary fibrosis.
Diabetes Diabetes and HbA1C ≥58mmol/mol
Immunocompromised Severe immunocompromise due to disease or treatment, for example: · transplantation: - Listed for solid organ or haematopoietic stem cell transplant (HSCT) - Post solid organ transplant at any time - Post HSCT within 12 months · genetic diseases: - APECED** - Inborn errors in the interferon pathway · treatment: - included but not limited to Cyclophosphamide, Rituximab, Alemtuzumab, Cladribine or Ocrelizumab in the last 6 months
Inherited metabolic diseases* Disorders of intermediary metabolism/at risk of acute decompensation, for example: Maple Syrup Urine Disease.